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Home  ::  Research & Development  ::  Departments  ::  Development :: Pharmaceutics  
 

 

Pharmaceutics ::

This department concerns itself with the development of conventional and novel dosage therapeutic forms, NDDS, formulations for toxicity studies, stability studies, and technology transfer to the production facility. All the activities are carried out as per Good Laboratory Practices and Good Manufacturing Practices. The facilities exist both for:

  • Laboratory Scale Development
  • Pilot Scale Development

Pharmaceutics is equipped with state of the art facilities to carry out formulation development of various conventional dosage forms and Novel Drug Delivery systems for known and new molecular entities for commercialization including:

  • Coated & Uncoated Tablets
  • Dispersible Tablets
  • Chewable Tablets
  • Hard & Soft Gelatin Capsules
  • Small and Large Volume Parenterals
  • Liquid Orals
  • Ointments / Creams
  • Dry Mixtures.

Development of Novel Dosage Forms is possible using following technologies:

  • Matrix and Diffusion
  • Controlled Drug Release
  • Microencapsulation
  • Osmotic Delivery
  • Pelletization
  • Powder Coating
  • Extrusions Spheronization
  • Air Suspension Coating
  • Multilayered Tablets

Major Activities :

The major activities of the department involve development of diverse range of formulations of potential molecules. Formulation Development activities are as follows:

Pre-formulation Studies

Development Trials

Trial Batches

Packing of Batch

Stability Studies

Scale-up Batch

Technology Transfer

The department also provides formulation development support to Torrel Cosmetics.

Formulations Commercialized:

The following products have been developed and commercialized in recent years.

TORRENT PHARMACEUTICALS
Conventional Dosage Forms

  • Cefixime 200/400 mg Tablets
  • Sultamicillin 375 mg Tablets
  • Lomefloxacin 400 mg Tablets
  • Nifedipine Soft Gelatin 5/10mg capsules
  • Ondansetron (4/8 mg) Tablets
  • Diclofenac Diethyl Ammonium 1% Gel
  • Pefloxacin 400 mg Tablets
  • Cefuroxime Sodium 250/750 mg Injection
  • Diltiazem Injection 5mg/ml
  • Haloperidol Intramuscular 50mg/ml Injection
  • Sodium Valproate 500 mg Alkalets
  • Pefloxacin 400mg/100ml Infusion
  • Metronidazole 500mg/100ml Infusion
  • Isosorbide Mononitrate 10/20/40 mg Tablets
  • Clozapine 25/100 mg Tablets
  • Ciprofloxacin Ophthalmic 0.3% Solution
  • Ciprofloxacin Infusion 200 mg/100ml
  • Fluconazole 2mg/ml Infusion
  • Terazosin 1/2/5 mg Tablets
  • Clonazepam 0.5/2 mg Tablets
  • Secnidazole 500 mg Tablets
  • Amlodipine Besylate 5/10mg Tablets
  • Piracetam 800 mg Tablets
  • Lisinopril + Hydrochlorothiazide (5+12.5mg), (10+12.5mg) Tablets
  • Lovastatin 20 mg Tables
  • Clomipramine HCl 25/50 mg Tablets
  • Ketoconazole Shampoo
  • Sparfloxacin 200/400 mg Tablets
  • Rosiglitazone 1/2/4/8 mg Tablets
  • Amlodipine + Losartan Potassium (5+50mg) Tablets
  • Losaratn Potassium + Hydrochlorothiazide Tablets(50+5mg) Tablets
  • Cefixime 100/200mg Tablets
  • Domperidone + Cinarazine (15+20mg) Tablets
  • Ormeloxifine 60mg Tablets
  • Repaglinide 0.5/1/2mg Tablets
  • Cetirizine 5mg/5ml Syrup
  • Nicorandil 5/10 mg Tablets
  • Ciprofloxacin 250/500/750 mg Tablets
  • Risperidone 1/2/3/4 mg Tablets
  • Danazol 50/100/200 mg Capsules
  • Famotidine 10mg Chewable Tablets
  • Piracetam 200mg/ml Injection
  • Imipramine 75mg Tablets
  • Cisapride & Methyl Polysiloxane (10mg + 125mg) Tablets
  • Carbamazepine Chewable Tablets 100 mg
  • Domperidone 10mg Tablets
  • Aciclovir 800mg Dispersible Tablets
  • Cefixime 50mg DT
  • Famotidine Chewable Tablets
  • Ondensetron 2ml/4ml Injection
  • Famotidine film coated 20&4omg Tablets
  • Ranitidine 150/300mg Tablets
  • Lopamide 2mg Tablets
  • Amoxicillin 250/500mg Capsules
  • Timolol Ophthalmic (0.25/0.5%) solution
  • Paracetamol + Dicofenac Sodium (500+50mg) Tablets
  • Atenolol 50/100mg Tablets
  • Lisinopril 2.5/5/10mg Tablets
  • Alprazolam 0.25/0.5mg Tablets
  • Diltiazem 30 and 60 mg Tablets
  • Roxithromycin 150mg Tablets
  • Cefadroxil Oral 125mg/5ml Suspension
  • Cefadroxil 500/100mg Tablets
  • Isoniazide 300mg Tablets
  • Mebendazole 100mg Tablets
  • Chloroquine Phosphate 250mg Tablets
  • Ketoconazole 200mg Tablets
  • Fluconazole 50/100/150/200mg Capsules
  • Norfloxacin 400mg Tablets
  • Nalidixic Acid 500mg Tablets
  • Lamotrigine 25/50/100mg Tablets
  • Sertraline 50/100mg Tablets
  • Losartan Potassium 25/50mg Tablets
  • Fluconazole Eye Drops
  • Nicorandil Injection 2/48 mg
  • Ciprofloxacin + Tinidazole Tablets
  • Carvedilol 6.25/12.5 mg Tablets
  • Iron and Folic Acid (50mg + 175mcg ; 100mg + 350mcg) Tablets
  • Iron Syrup 50mg/5ml
  • Mosapride 2.5/5mg Tablets
  • Venlafaxine 37.5/75mg Tablets
  • Sildenafil 25/50/100mg Tablets
  • Clopidogrel 75mg Tablets
  • Sibutramine HCl 5/10mg Capsules
  • Fexofenadine 120/180mg Tablets

New Drug Delivery Systems :

Torrent's Novel Drug Delivery research is focused on the development of innovative new drug delivery technologies. By combining our development expertise with state of the art infrastructure, we are creating successful clinical products, both branded and generics, for the benefit of patients around the globe. We have applied our drug delivery technologies for many blockbuster molecules and our own New Chemical Entities (NCE's) to develop dosage forms with enhanced therapeutic benefit. Currently, we are dedicated to pioneer the concept of advanced drug delivery through our focused research in thrust areas like Multiparticulate oral delivery, Osmotically engineered systems, Gastro-retentive release modulating devices, Mucoadhesive systems, Hydrogel matrix formulations, Melt-in Mouth tablets and Transdermal drug delivery systems.

Multiparticulate Oral Delivery :

  • Diltiazem ER Pellets
  • Omeprazole delayed release pellets
  • Lansoprazole delayed release pellets
  • Venlafaxine ER pellets
  • Esomeprazole delayed release pellets

Hydrogel Matrix Systems :

  • Nifedipine Retard
  • Isosorbide 5-mononitrate SR
  • Alprazolam SR
  • Sodium Valproate SR
  • Carbamazepine CR
  • Varapamil SR
  • Lithium Carbonate ER
  • Diclofenac Sodium SR

Multiple Layer Matrix Systems :

  • Isosorbide 5-mononitrate SR + Aspirin
  • Alprazolam SR + Sertraline HCl

Melt -in-Mouth System :

  • Mosapride MT
  • Domperidone MT

Inlay Tablet :

  • Rosiglitazone IR + Metformin SR Tablet

Dispersible Formulations :

  • Amoxycillin Dispersible 125mg Tablet
  • Cefadroxil Dispersible 125/250mg Tablet
  • Roxithromycin Dispersible 50mg Tablet
  • Domperidone Dispersible 5/10mg Tablet


T orrel Cosmetics :

  • Soothing Cleansing Milk - With Calendula Plant Extract
  • Refreshing Toner - Alcohol-Free With Witch Hazel Distillate
  • Comprehensive Revitalising System - Revitalising, Moisturing and Protecting Cream With AhA
  • Integrated Nourishing System - Nourishing Cream with Efas, Vitamin A & E
  • Alpha Moisturising Lotion - Moisturising and Protecting Lotion with AhA
  • Care Cream for Pimple-Prone Skin - With UV Filters, Vitamin A,E, and Disinfectants
  • Fairness Formula for Sensitive Skin - Cream with Natural Fairness Enhancer and UV Filters
  • Tropical Sunscreen Lotion
  • Ceramide Complex Concentrate - Intensive Skin Care for Face and Throat with Ceramides, Vitamin A, E and EFAs
  • Ceramide Complex Cream - Intensive Skin Care Face and Throat with Ceramides, Vitamin A,E and EFAs
  • Soothing Body Lotion - With Calendula Plant Extract
  • Tropical Sunscreen Lotion
  • Ceramide Complex Concentrate - Intensive Skin Care for Face and Throat with Ceramides, Vitamin A, E and EFAs
  • Ceramide Complex Cream - Intensive Skin Care Face and Throat with Ceramides, Vitamin A,E and EFAs
  • Soothing Body Lotion - With Calendula Plant Extract


 
 
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